1978.3-1982.12  浙江医科大学医学系本科学生，获学士学位。1985.9-1988.7 苏州医学院医学遗传学专业硕士研究生，获硕士学位。长期从事临床遗传学、产前遗传学诊断、辅助生殖、着床前遗传学诊断等工作。1990.9-1991.6 CMB-HKU奖学金获得者，香港大学医学院妇产科系访问学者，从事产前遗传学诊断研究工作。1997.10.-1998.11 澳大利亚Adelaide大学妇产科系访问学者，从事比较基因组杂交着床前胚胎遗传学研究。2002.11- 2003.11，2005.1.-2005.8，2008.10-2009.2 美国MAYO医学中心内分泌研究所和妇产科系访问学者，从事生殖内分泌研究。已在国内外重要杂志上发表论文60余篇，著有医学遗传学、生殖医学等专著4部。负责国家重大研究计划项目课题2项目、国家自然科学基金项目一项,浙江省自然科学重点项目等省部课题3项，获国家科学技术进步二等奖一项(第六),省科技进步一等奖二次(第二,第五),省科技进步二等奖二次(第一,第四)。
近期以通信作者身份发表论文:
（1）Altered expressions and DNA methylation of imprinted genes in chromosome 7 in brain of mouse offspring conceived from in vitro maturation. Reprod Toxicol. 2012；34：420– 428
（2）A large deletion/insertion-induced frameshift mutation of the androgen receptor gene in a family with a familial complete androgen insensitivity syndrome. Gene. 2012 Jun 1;500(2):220-3.
（3）Preimplantation and prenatal genetic diagnosis for androgen insensitivity syndrome resulting from a novel deletion/insertion mutation. Clin Genet. 2012 Feb 14. doi:10.1111/j.1399-0004.2012.01847.x.
（4）Meiotic segregation analysis of embryos from reciprocal translocation carriers in PGD cycles. Reprod Biomed Online. 2012 Jan;24(1):83-90
（5）Different sperm sources and parameters can influence intracytoplasmic sperm injection outcomes before embryo implantation. J Zhejiang Univ Sci B. 2012Jan;13(1):1-10.
（6）Altered expression of Armet and Mrlp51 in the oocyte, preimplantation embryo, and brain of mice following oocyte in vitro maturation but postnatal brain development and cognitive function are normal. Reproduction. 2011 Sep;142(3):401-8.
（7）Genome-wide DNA Methylation Patterns in IVF-conceived Mice and their Progeny: A putative model for ART-conceived humans. Reprod Toxicol. 2011 Jul; 32 (1):98– 105
（8）Evaluation of DNA methylation status at differentially methylated regions (DMRs) in IVF-conceived newborn twins. Fertil Steril. 2011 May; 95(6):1975-9.
（9）Normal epigenetic inheritance in mice conceived by in vitro fertilization and embryo transfer. J Zhejiang Univ Sci B. 2011 Oct;12(10):796-804.
（10）Cri du chat syndrome after preimplantation genetic diagnosis for reciprocal translocation. Fertil Steril. 2011 Jul;96(1):e71-5.